Document Type

News Article


The release of cytokines due to astrocyte and microglial activation could progress towards the most anticipated cytokine storm proving to be detrimental in the management of COVID-19.

· Such hyper-inflammatory conditions could make the BBB vulnerable, encouraging excessive viral particles into the CNS, leading to further neurodegenerative pathologies like Alzheimer’s disease, Parkinson’s disease, Creutzfeldt-Jakob disease, and Multiple Sclerosis.

· Excessive neuroinflammation and neurodegeneration being the anticipated root causes of these multiple conditions, it is also essential to investigate other factors that synergistically enhance the worsening of these diseases in COVID-19 patients for which additional studies are essential.

Publication Date