Animal models of chemotherapy-induced cognitive decline in preclinical drug development

Document Type

News Article


Ø Chemotherapy-induced cognitive impairment (CICI), also known as chemobrain or chemofog, refers to the mental dysfunction experienced by cancer patients/survivors undergoing chemotherapy treatment

Ø The publication emphasizes the importance of understanding the mechanisms underlying CICI to develop effective therapeutic interventions for its alleviation

Ø Animal models play a crucial role in investigating and elucidating the underlying mechanisms of CICI, providing a valuable tool for studying different treatment hypotheses and strategies

Ø The use of animal models in preclinical drug development allows for critical evaluation and validation of potential treatments targeting CICI

Ø The publication also highlights the significance of animal models in advancing our understanding of CICI and facilitating the development of novel therapeutic approaches to mitigate its impact on cancer patients/survivors

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