Date of Award

Winter 4-1-2019

Document Type


Degree Name

MPharm Pharmacy Practice


Department of Pharmacy Practice

Second Advisor

Dr. Sreedharan Nair

Third Advisor

Dr. Muralidhar V Pai


Objective of the study was to evaluate the drug utilization pattern in pregnancy. A retrospective study conducted among pregnant women in a tertiary care teaching hospital. Parameters like demography, gravidity, complaints on admission, clinical signs and symptoms, comorbid conditions, drugs prescribed and its utilization details and neonatal outcome were collected. Study included 876 pregnant women. The mean age of the study population was 29.4±4.4 (mean±SD). Majority of them (68.2%) had caesarian section type of delivery. Diabetes mellitus (33.6%) was the most common comorbidity, followed by hypertension (28.3%) and thyroid disorders (18.3%). Folic acid (15.7%) and calcium (15.2%), were the most commonly prescribed drugs, followed by ferrous fumarate (7.1%), vitamin B12 (5.3%) and vitamin B6 (3.4%). In terms of DDD/100 bed days, levothyroxine (369.3) was the most commonly utilized drug, followed by digoxin (53.6), dydrogesterone (27.4) and salbutamol (20.5). Levothyroxine was the most commonly utilized drugs among the study population because 18.3% of pregnant women had thyroid disorders. It is essential to treat thyroid disorders during pregnancy, otherwise, both pregnant women and fetus will have adverse consequences. Estradiol was only the FDA pregnancy category X drug prescribed and estradiol supplement is required to improve pregnancy rates after in vitro fertilisation.