Manipal Journal of Pharmaceutical Sciences


In the current widening global economy, failures can have profound impact on an organization’s competitiveness. To be successful in business, every organization focuses on how to prevent failures in their manufactured products, processes, and operations. To reduce the loss, the only way out is to investigate their cause and prevent it from reoccurrence. Root cause analysis is an effective method to achieve this particular goal. Root cause analysis is a technique to address a non-conformance or problem to find out the real cause of particular problem. For investigation, various root cause analysis tools are used. The main aim of root cause analysis is to discover the actual cause of an observed problem, defect, or failure so as to utilize this particular information to correct it. After the investigation and identification of appropriate root cause the implementation of CAPA (Corrective Action and Preventive Action) should be done