The Use of Green Inhibitors in Evaluating the Safe Expiry Dates of Therapeutics

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Journal of Bio- and Tribo-Corrosion


The present work was done with dual intentions. The primary aim was to attenuate the acid corrosion of 6061 aluminum alloy by green approach. While doing so, an attempt was made to use the expiry date pharmaceutical product Streptomycin (SEPT) injection. This unique method could provide the best possible pathway for the utility of otherwise useless, non-eco-friendly expiry date drugs. Corrosion inhibition studies were performed using electrochemical techniques. Experimental settings were augmented to attain the highest possible efficacy of SEPT by changing its concentration and temperature. Experimental values were close-fitted into proper adsorption isotherm. Surface morphology studies like SEM and AFM were performed to confirm the adsorption of inhibitor. Streptomycin emerged as an exceptionally good inhibitor with an efficacy of 77% for the addition of just 1 ppm of the inhibitor at 303 K. Outcome of the work provided a unique pathway for utility expiry date drug, thereby minimizing the environmental pollution.



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