Mucinous tubular and spindle cell carcinoma a review of histopathology and clinical and prognostic implications
Archives of Pathology and Laboratory Medicine
Mucinous tubular and spindle cell carcinomas are rare kidney tumors with generally indolent behavior. As the name suggests, classic histomorphology reveals bland spindle cells, tubules, and mucinous stroma. Uncommon histologic features include mucin-poor stroma, high nuclear grade, cellular pleomorphism, and presence of necrosis. Rare cases can show aggressive growth and distant metastasis. Mucinous tubular and spindle cell carcinoma has characteristic chromosomal abnormalities and the molecular signature remains the same, irrespective of the varied histomorphology.
Nathany, Shrinidhi and Monappa, Vidya, "Mucinous tubular and spindle cell carcinoma a review of histopathology and clinical and prognostic implications" (2020). Open Access Archive. 433.