Retention of moisture-tolerant fluoride-releasing sealant and amorphous calcium phosphate-containing sealant in 6-9-year-old children: A randomized controlled trial

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Journal of Indian Society of Pedodontics and Preventive Dentistry


Context: Pits and fissures of teeth have been recognized as the most susceptible areas for initiation of caries. The ability of the resin sealant to thoroughly fill pits, fissures, and/or morphological defects and remain completely intact and bonded to enamel surface is the primary basis for its caries prevention. Aim: The present study evaluated and compared the retention rates and development of caries in permanent molars of children sealed with amorphous calcium phosphate‑containing (Aegis™) and moisture‑tolerant fluoride‑releasing (Embrace WetBond™) sealant over a period of 1 year. Settings and Design: This was a double‑blind, split‑mouth, randomized controlled trial among children aged 6-9 years. Methods: Sixty‑eight permanent mandibular first molars in 34 children were randomly assigned to be sealed with Aegis™ or Embrace Wetbond™ sealant. The follow‑up examinations were conducted at 3, 6, and 12 months for evaluating the retention and development of caries. Statistical Analysis: SPSS version 16.0 was used for the analysis. Within‑group comparison of retention and development of caries at 3, 6, and 12 months was evaluated using the Friedman's test. Results: The final sample was 32 children with 64 teeth. At 12 months, 23 of 32 (72%) sealants were completely retained in Aegis™, whereas 21 of 32 (65.6%) were retained in Embrace Wetbond™ group. There was no significant difference in the retention rates of Aegis™ and Embrace Wetbond™ sealants at 12 months (P > 0.05). Conclusion: Aegis™ was superior to Embrace Wetbond™ sealant as Aegis™ exhibited higher retention and lower caries scores.

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