Date of Award

Winter 1-4-2019

Document Type

Dissertation

Degree Name

MPharm Pharmacy Practice

Department

Department of Pharmacy Practice

First Advisor

Dr. Shubha Sheshadri

Third Advisor

Girish Thunga

Abstract

Background –Diabetes is a chronic, metabolic disorder that is characterized by resulting from defects in insulin secretion, insulin action or both which will affect the patient Quality of life. Pharmaceutical Care is the responsible provision of drug therapy for of achieving definite therapeutic outcomes that improve the patient‘s quality of life.It contributes to the resolution of medical conditions and can help avoid undesirable outcomes about patient‘s drug therapy problems, resulting in benefits to patients.Objectives –To study the impact of Pharmaceutical care in type 2 diabetic patients in a tertiarycare hospital.Methodology –A prospective interventional study was conducted for a period of 8 months, after taking ethical committee approval. Total of 104patients were selected, 52 patients in the Intervention group and 52 patients in the usual medical care group as per the inclusion criteria from medicine ward 2 and 4 of tertiary care hospital. Demographic characteristics were documented in the data collection form and the patients were administered with Modified Diabetes Quality of life questionnaire (MDQoL)and Knowledge, Attitude and practice questionnaire (KAP)questionnaire in the different languages which issuitable for the patientsafter admission to hospital, before discharge, during first and second follow-up.Out of 52 patients in the intervention group 24 patients completed both 1rstand 2ndfollow up and in the control group among 52 patients, 12 patients completed the both the follow-up. Data was analyzed using IBM SPSS 20version.Results –Out of 104 DM patients from both the group majority of the study population were male, overall number of male patient in both the group is 78( 75.01%). The average age of study population was 61.38±12.2 years and majority of the patient had a diabetes history of more than 5 years and HbA1c value of intervention group was 6.65±0.83%and for control group 7.42±0.80%.FBS level was120.87±23.86 mg/dL in the intervention group and 123±33.07 mg/dLin the control group.Majority of patientsin the intervention group had MDQoL score >70 andcontrol group patients had MDQoL score between 50 -70.There is improvement in the knowledge;attitude and practice(KAP)score in the intervention groupthan that of control group. We observed there was statistically significant increase inMDQoL score and KAP score of intervention groupfrom day of admission to 2ndfollow up.(P<0.00)Conclusion–The study concludes that the providing Pharmaceutical care to the DM patients will improve the quality of life, knowledge and also control glucose levelin diabetic patients.

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