Unusual Extramedullary Presentation of Mixed Phenotype Acute Leukemia – A Case Report

Authors

Hasmukh Jain, Department of Medical Oncology, Tata Memorial Centre, Department of Medical Oncology, E. Borges Road, Parel (E), Mumbai 400012.Follow
Manju Sengar, Department of Medical Oncology, Tata Memorial Centre, Department of Medical Oncology, E. Borges Road, Parel (E), Mumbai 400012.Follow
Hari Menon, Department of Medical Oncology, Tata Memorial Centre, Department of Medical Oncology, E. Borges Road, Parel (E), Mumbai 400012.Follow
Tanuja Shet, Department of Pathology. Tata Memorial Centre, Department of Medical Oncology, E. Borges Road, Parel (E), Mumbai 400012.Follow
Raajit Chanana, Department of Medical Oncology, Tata Memorial Centre, Department of Medical Oncology, E. Borges Road, Parel (E), Mumbai 400012.Follow
Uma Dangi, Department of Medical Oncology, Tata Memorial Centre, Department of Medical Oncology, E. Borges Road, Parel (E), Mumbai 400012.Follow

Abstract

Mixed phenotype acute leukemia (MPAL) is a rare subtype of acute leukemia. The clinical manifestations are both due to bone marrow failure and extramedullary sites of involvement which can lead to protean manifestations. Accurate and timely diagnosis needs clinical suspicion as well as collaboration with the hematopathologist. Extramedullary (EM) disease poses a unique therapeutic challenge. There is a need for more data to guide treatment decisions and justify the usefulness of radiation and allogeneic stem cell transplant. We present 3 cases of MPAL with unusual EM sites of involvement.

Recommended Citation

Jain, Hasmukh; Sengar, Manju; Menon, Hari; Shet, Tanuja; Chanana, Raajit; and Dangi, Uma (2016) "Unusual Extramedullary Presentation of Mixed Phenotype Acute Leukemia – A Case Report," Manipal Journal of Medical Sciences: Vol. 1: Iss. 1, Article 8.
Available at: https://impressions.manipal.edu/mjms/vol1/iss1/8