Glycemic Control and Its Relationship Between Lipid Profiles and Thyroid Profiles: Insights from a Case? Control Study from Coastal Karnataka, South India

Document Type

Article

Publication Title

Universal Journal of Public Health

Abstract

Introduction: In India, the burden of diabetes mellitus is rising swiftly, mirroring a global trend that is being observed in both developed and developing countries. Examining the correlation between indices of glycemic status & thyroid and lipid parameters at different glycemic control levels was the goal of the present study. Methods: This case control study included 50 cases (HbA1c > 6.5 %) and 150 controls (HbA1C < 6.5) who were attending an executive health check up at a tertiary level health care hospital attached to a medical college in a coastal city in Southern India. Glycemic indices, thyroid profile and lipid profile were evaluated. Correlation analyses, t-tests, and chi-square tests were carried out. Results: Cases had a mean age of 57.80±10.71 years whereas controls had a mean age of 48.47±13.89 years. The cases and controls did not have discernable differences in the lipid profile characteristics. However, T4 and HbA1C (Glycated Hemoglobin), depicted a weak positive correlation with the value of correlation coefficient r= 0.211 (p= 0.014). With respect to T4, there was a higher mean rank contrast observed among the cases than that of controls (p=0.014). Conclusion: A positive association between thyroid hormone T4 levels and glycemic status was found in this study, even if no correlation was found between glycemic control and lipid profile. This research lays emphasis on closely observing thyroid function in addition to glycemic parameters for the all-encompassing control of diabetes mellitus.

First Page

861

Last Page

866

DOI

10.13189/ujph.2024.120509

Publication Date

10-1-2024

This document is currently not available here.

Share

COinS