A Custom Deep Learning Model With Explainable Artificial Intelligence for Interpretable Brain Tumor Classification
Document Type
Article
Publication Title
Engineering Reports
Abstract
Brain tumors are critical neurological disorders affecting mankind. The Magnetic Resonance Imaging (MRI) and Computed Tomography (CT) scans play an important role in diagnosing brain tumors, but need an expert interpretation. Although deep learning methods can automate tumor detection, their lack of interpretability and clinical trust remains a major limitation. To address this concern, this paper presents a BrainTumorClassificationNetwork-Convolutional Neural Network (BTCNet-CNN) model with several layers for detecting and classifying MRI scanned images into four categories: glioma, meningioma, no tumor, and pituitary. The model was trained and evaluated on a publicly available dataset comprising 5824 MRI images. Augmentation techniques such as horizontal flipping, random rotations, zooming, shifting, and shearing were implemented on the training set, increasing data diversity and enhancing BTCNet-CNN's robustness to variations in tumor orientation, scale, and position. To evaluate the effectiveness of the proposed model, various popular pre-trained networks such as ResNet50 and InceptionV3 are also implemented on the dataset with metrics such as accuracy, loss, precision, recall, F1 score, and AUROC. Among these three models, the BTCNet-CNN has achieved superior performance with an accuracy of 99.31%, a loss of 0.118, and an average precision, recall, and F1 score of 99.25%, 99.25%, and 99.5%, respectively, on the unseen data. Statistical significance was evaluated using McNemar's test, confirming that BTCNet-CNN's predictions are significantly better than those of ResNet50 and InceptionV3 (p < 0.05). To enhance trust and interpretability of models' decisions, various Explainable AI (XAI) techniques, including Occlusion Sensitivity, LIME, Smooth Gradients, and Saliency Maps, were integrated. Finally, a Streamlit-based web application was developed to facilitate real-time prediction and visualization, ensuring practical applicability in clinical diagnosis.
DOI
10.1002/eng2.70515
Publication Date
12-1-2025
Recommended Citation
Rohan, Duppala; Yaswanth, Boddepalli; Vardhan, V. S.Sai; and Reddy, G. Pradeep, "A Custom Deep Learning Model With Explainable Artificial Intelligence for Interpretable Brain Tumor Classification" (2025). Open Access archive. 11963.
https://impressions.manipal.edu/open-access-archive/11963
