Neonatal thyrotoxicosis with maternal hypothyroidism

Document Type

Article

Publication Title

BMJ Case Reports

Abstract

Neonatal Graves' is uncommon, but a potentially fatal condition caused by transplacental transfer of thyroid stimulating immunoglobulin (TSI). It is seen in 1%-5% of infants born to a mother with Graves' disease. Here, we report a unique case of transient neonatal thyrotoxicosis with positive TSI in a premature neonate born to the mother with primary hypothyroidism. A short course of antithyroid drug treatment leads to significant clinical and biochemical improvement followed by complete recovery.

DOI

10.1136/bcr-2021-247865

Publication Date

3-9-2022

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