CRISPR/Cas based gene editing: marking a new era in medical science
Document Type
Article
Publication Title
Molecular Biology Reports
Abstract
CRISPR/Cas9 system, a bacterial adaptive immune system developed into a genome editing technology, has emerged as a powerful tool revolutionising genome engineering in all branches of biological science including agriculture, research and medicine. Rapid evolution of CRISPR/Cas9 system from the generation of double strand breaks to more advanced applications on gene regulation has made the wide-spread use of this technology possible. Medical science has benefited greatly from CRISPR/Cas9; being both a versatile and economical tool, it has brought gene therapy closer to reality. In this review, the development of CRISPR/Cas9 system, variants thereof and its application in different walks of medical science- research, diagnostics and therapy, will be discussed.
First Page
4879
Last Page
4895
DOI
10.1007/s11033-021-06479-7
Publication Date
5-1-2021
Recommended Citation
Prasad, Kirti; George, Anila; Ravi, Nithin Sam; and Mohankumar, Kumarasamypet M., "CRISPR/Cas based gene editing: marking a new era in medical science" (2021). Open Access archive. 2859.
https://impressions.manipal.edu/open-access-archive/2859
