A Systematic Review on Temporal Lobe Epilepsy Patients with Corona Virus Infection

Document Type

Article

Publication Title

Journal of Angiotherapy

Abstract

Objective: To systematically review the neurological symptoms and complications in temporal lobe epilepsy patients with Coronavirus infected patients. Methods: A systematic review of clinical studies on cases with neurological symptoms linked to COVID-19 and other coronaviruses was conducted. Following the PRISMA guidelines, a search for related scientific publications was performed in the following electronic databases: PubMed, Scopus, and Embase. The keywords used were “coronavirus" or "Sars-CoV-2" or "COVID-19" and "neurologic manifestations" or "neurological symptoms" or "meningitis" or "encephalitis" or "encephalopathy." Results: A total of 43 articles varying from case reports to case series, cohort studies, and systematic reviews were examined on SARS-CoV-2 and other human coronavirus infections with clinical symptoms in the central nervous system. Hyposmia, headaches, weakness, and altered awareness were among the most commonly reported symptoms. COVID-19 has been linked to encephalitis, demyelination, neuropathy, and stroke. Infection via the cribriform plate of the ethmoidal bone and olfactory bulb, as well as trans- synaptic transmission, are some of the proposed mechanisms. Invasion of the medullary cardiorespiratory center by SARS-CoV-2 may have a role in the refractory respiratory failure seen in corona virus-infected patients who are critically ill. Conclusion: Coronaviruses have a high potential to damage the central nervous system and can cause a variety of neurological symptoms, from moderate to severe. cephalalgy, lightheadedness, and altered level of consciousness were the most common neurological functional and structural signs discovered.

First Page

632

Last Page

636

DOI

10.25163/angiotherapy.6221312825042022

Publication Date

1-1-2022

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