A NEW MICROWAVE-ASSISTED METHOD FOR THE SYNTHESIS OF 2-SUBSTITUTED-THIAZOL-4(5H)-ONE VIA HANTZSCH CONDENSATION
Document Type
Article
Publication Title
Rasayan Journal of Chemistry
Abstract
A new microwave-assisted method is developed for the synthesis of 2-substituted-thiazol-4(5H)-ones via Hantzsch condensation by a simple experimental protocol without using any catalyst. The products were isolated in excellent yield without any purification. Synthesized compounds were characterized by applying FTIR,1 H NMR,13 C NMR, and mass spectral studies and a plausible mechanism is proposed for the formation of the product. The method is versatile for the preparation of a new class of 2-substituted-thiazol-4(5H)-ones.
First Page
310
Last Page
315
DOI
10.31788/RJC.2022.1516578
Publication Date
1-1-2022
Recommended Citation
Nayak, Swarnagowri and Gaonkar, Santosh L., "A NEW MICROWAVE-ASSISTED METHOD FOR THE SYNTHESIS OF 2-SUBSTITUTED-THIAZOL-4(5H)-ONE VIA HANTZSCH CONDENSATION" (2022). Open Access archive. 5078.
https://impressions.manipal.edu/open-access-archive/5078
