Summary of - Kadukkai maathirai (Siddha herbal formulation) reverses liver pathology associated with metabolic dysfunction in high fat diet-induced fatty liver disease – a preclinical study

Document Type

Article

Abstract

The effect of Kadukkai maathirai (KM) in high fat diet (HFD) induced nonalcoholic fatty liver disease (NAFLD) in Sprague Dawley rats was evaluated. Nine groups of rats were used as follows: Group I – normal control, II – IV test drug control and group V- HFD induced NAFLD disease model. Group VI – IX received HFD for 40 weeks followed by KM in three different doses (group VI – VIII) and metformin (group IX) for 45 days. Blood sample and liver were collected for analysis. KM could reverse most of the HFD induced alterations in metabolic and hepatic dysfunction related parameters.

Publication Date

2023

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