Summary of - Naturally occurring anti-kpa in an infant with recurrent bacterial infection: a case report and review of the literature
Document Type
Article
Abstract
Naturally occurring anti-Kpa antibody is extremely rare and was first reported in 1957, named after the first producer ‘Penney’. However, the subsequent anti-Kpa reports presented were all anti-Kpa due to isoimmunization. Individuals with severe bacterial infections particularly Gram-negative bacteria are known to be capable of producing cross-reactive antibodies against Kell blood group system. However, such uncommon antibodies like anti-Kpa can be easily missed in routine pre-transfusion testing unless the panel cells containing low incidence antigen are used for antibody screening. Here, we report a case of naturally occurring anti-Kpa antibody, identified incidentally during pre-transfusion testing of a 12-month-old female infant with the diagnosis of Niemann–Pick disease and recurrent bacterial (Escherichia coli) infection.
Publication Date
2022
Recommended Citation
Kandasamy, Dhivya; Shastry, Shamee; Chenna, Deepika; Prethika, Ponniah Amutha; Vaidya, Ashwinkumar; and Rajendran, Vinu, "Summary of - Naturally occurring anti-kpa in an infant with recurrent bacterial infection: a case report and review of the literature" (2022). Open Access archive. 9303.
https://impressions.manipal.edu/open-access-archive/9303
