Insulin autoimmune syndrome: A rare cause of spontaneous hypoglycaemia in non-diabetic individuals
Document Type
Article
Publication Title
BMJ Case Reports
Abstract
Insulin autoimmune syndrome (IAS) is a rare cause of hypoglycaemia, characterised by recurrent hypoglycaemic episodes secondary to insulin autoantibodies in individuals who are not exposed to exogenous insulin. We are reporting a case of IAS in a 64-year-old gentleman, who presented with predominant postprandial hypoglycaemic episodes. On biochemical evaluation, he was found to have hyperinsulinemic hypoglycaemia. Localisation studies with MRI abdomen and endoscopic ultrasound (EUS) were negative for pancreatic tumour. Tests sent for insulin antibody levels were elevated. The patient was treated with frequent meals, acarbose and glucocorticoids. Patient condition improved and did not experience hypoglycaemia on follow-up.
DOI
10.1136/bcr-2020-234448
Publication Date
12-9-2020
Recommended Citation
Ravindra, Shruthi and Shetty, Sahana, "Insulin autoimmune syndrome: A rare cause of spontaneous hypoglycaemia in non-diabetic individuals" (2020). Open Access archive. 969.
https://impressions.manipal.edu/open-access-archive/969
