Polymeric Nanostructures Revolutionizing Cervical Cancer: Diagnostics, Therapeutics, and Theranostics
Document Type
Article
Publication Title
BioNanoScience
Abstract
Cervical cancer is the fourth most common cancer among women. Despite recent advancements in diagnostics and therapeutics, this disease is still a formidable challenge to deal with. Conventional methods for detecting human papillomavirus infection and imaging the tissues face major hurdles due to a lack of signal specificity and obscured resolution respectively. Moreover, chemotherapeutics struggle against the development of multidrug resistance and rapid clearance. With their easily tunable properties, polymeric nanostructures present a promising avenue for rapid, specific, and efficient diagnostics and therapeutics. These nanostructures also serve as theranostic agents that integrate imaging modalities with therapeutic approaches concurrently. This review highlights various types of polymeric nanostructures that serve as biosensors for the detection and quantification of cervical cancer biomarkers and act as nanocarriers for transporting fluorophores, photosensitizers, drugs, and radiosensitizers to their target site of action. Graphical Abstract: (Figure presented.)
First Page
3906
Last Page
3933
DOI
10.1007/s12668-024-01496-9
Publication Date
11-1-2024
Recommended Citation
Dey, Bipasa; Kundu, Soubarno; and Sundara, Babitha Kampa, "Polymeric Nanostructures Revolutionizing Cervical Cancer: Diagnostics, Therapeutics, and Theranostics" (2024). Open Access archive. 9920.
https://impressions.manipal.edu/open-access-archive/9920
