Seroprevalence of SARS-CoV-2 IgG antibodies in health care workers and the associated risk factors during the covid-19 pandemic period at a tertiary care heatlh center in South India
Document Type
Article
Publication Title
IP International Journal of Medical Microbiology and Tropical Diseases
Abstract
Background: Most of the published studies across the globe so far have demonstrated a highly variable seroprevalence rate of SARS-CoV-2 IgG antibodies in health care workers [HCW’s] during the pandemic period. Multiple risk factors were studied that influenced the seropositivity. Aim & Objective: The primary aim of the study was to determine the seroprevalence of SARS-CoV-2 IgG in HCW’s in local settings during the pandemic period. The secondary objective was to categorize the HCW’s based on the history of symptoms of covid-19 and also to evaluate the relation between the various risk factors and seropositivity amongst the HCW’s. Materials and Methods: A cross sectional prospective study was conducted on health care workers at a tertiary care hospital in Telangana state during the pandemic period between March to April 2021. Following enrollment and verbal consent from the participants descriptive data was collected using a validated questionnaire. SARS-CoV-2 IgG antibodies estimation was done using ELFA technology after obtaining IERB clearance. Results: Of the 230 enrolled participants 141 [61.30%] fulfilled the inclusion criteria. The overall SARS-CoV-2 IgG seropositivity in the present study was 48 [34.04%]. Of the 72 [51.06%] symptomatic HCW’s, 19 [26.38%] were seropositive and of the 69 [48.93%] asymptomatic, 29 [42.02%] were seropositive. Among the various risk factors studied none were found to be significantly associated with seropositivity. Conclusion: in the present study a greater number of asymptomatic HCW’s were found seropositive which could be due to several of the reasons discussed below one being silent transmission of the virus and demands further enquiry into the cause by improved research methodology.
First Page
329
Last Page
336
DOI
10.18231/j.ijmmtd.2024.056
Publication Date
10-1-2024
Recommended Citation
Fatima, Sarwat; Hazari, Ahmed Abdul Bari; and Handa, Deepika, "Seroprevalence of SARS-CoV-2 IgG antibodies in health care workers and the associated risk factors during the covid-19 pandemic period at a tertiary care heatlh center in South India" (2024). Open Access archive. 9944.
https://impressions.manipal.edu/open-access-archive/9944
